Calm ZZZ is designed for individuals who are under constant stress but also have a deficient constitution. This is one of the best formulas to treat shen (spirit) disturbance both during the day and at night. Shen (spirit) disturbance during the day can manifest as stress, anxiety and emotional instability. Shen (spirit) disturbance at night manifests as insomnia with difficulty falling asleep and/or staying asleep.